Longevity supplements: what science actually says

2026-03-28 · AEONUM

The truth about supplements

No supplement replaces good sleep, nutrition and exercise. That said, some have solid evidence as a complement to optimized habits.

Supplements with strong evidence

Vitamin D3 + K2 — most people are deficient. Affects 1000+ gene expressions.

Omega-3 (EPA/DHA) — anti-inflammatory, neuroprotective. 2-3g/day.

Magnesium (glycinate or threonate) — involved in 300+ enzymatic reactions.

Creatine — not just for muscle. Protects brain, improves cognition, 5g/day.

NMN or NR — NAD+ precursors, cellular energy. Promising but still under study.

Measure if they work with AEONUM

Track energy, sleep, body composition and habits before and after adding a supplement. AEONUM shows you if there's a real measurable change.